Postdoctoral Researcher Neety Sahu On Helping Patients With Osteoarthritis – Neety Sahu is a postdoctoral fellow in biomedicine at the prestigious Stanford University, and within a few years she has published a number of scholarly articles on her research in peer-reviewed medical journals.
Sahu’s advanced research focuses on osteoarthritis, a common and painful form of arthritis that affects millions of people in the United States alone.
Postdoctoral Researcher Neety Sahu On Helping Patients With Osteoarthritis
After its onset, osteoarthritis can affect the patient for the rest of his or her life, and as we will explain shortly, treatment options are primarily aimed at treating the painful symptoms of osteoarthritis. sick.
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There is no cure for the disease and this is bad news for everyone who is experiencing osteoarthritis symptoms now and who may develop it in the future, including millions of people.
Sahu is working to find better ways to treat osteoarthritis, and what we will focus on in this article is how she and her colleagues use modern technologies to conduct research. save this.
The first is to describe Sahu’s research goals. The main goal, of course, is to develop a better understanding of osteoarthritis itself.
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Yes, osteoarthritis is a known disease. Its common symptoms (joint pain, mainly in the hands, neck, knees and/or lower back) are well documented and, for patients with advanced osteoarthritis, these symptoms This can lead to a poor quality of life.
However, as Sahu confirmed when talking with us, no drugs to treat osteoarthritis have been found. Currently, osteoarthritis treatment options focus on pain control and symptom relief.
Sahu’s research efforts in this area include testing treatment options and identifying cellular-level red markers that indicate the presence of osteoarthritis.
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“This disease currently has no definitive treatment nor early diagnosis. To date, the potential drugs have failed miserably in clinical trials, despite showing successful results in previous studies in small animals. This is due to cellular and inter-patient differences in humans. I use single cell methods to map the effects of candidate drugs on patient-specific osteoblasts. I also use single-gene techniques to identify molecular markers for degenerative joint disease.
The study of these drugs and biological devices involves modern technology, and today we will explore these technologies and research with Sahu as our guide and resident expert. our.
The set of tools and methods required for Sahu’s research is known as single cell technology. Single-cell technology allows researchers and medical professionals to collect data at the cellular level, analyzing large numbers of individual cells to provide insights. The applications of this data are many, even in the diagnosis of osteoarthritis.
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Sahu: “Single-cell techniques provide insights into cell differentiation, identification of rare subpopulations, and cellular events. This information is important to open up answers to differences in disease progression, response to medication, and more.
For now, we would like to emphasize that single-cell technology is very important and moreover, the collection and analysis of these data would not be possible without the use of technical methods, especially Biology software.
Single-cell technology falls under the big umbrella of Big Data and as anyone involved in Big Data knows, collecting data is one thing, but analyzing that data to turn it into something easy. understanding and users is a great job.
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Given the size of these data, manual searching would be inefficient and in some cases nearly impossible. Human analysis can also cause more errors.
In contrast, professional software can analyze large amounts of data quickly, giving professionals more time to gain insights from that analysis.
Trying to manually search for this much information won’t work at least. Next, let’s see the impact of this type of research.
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As with many other diseases, early detection is very beneficial for the patient. Early detection means that steps can be taken to slow or stop the progression of the disease. Sahu explains that osteoarthritis begins to develop before symptoms can be measured.
“The factors that cause osteoarthritis occur years before the onset of clinical symptoms, such as pain and cartilage damage. Joint injuries such as ACL tears, etc., increase the risk of developing posterior osteoarthritis. Early research into osteoarthritis will help identify people with osteoarthritis at risk and possibly prevent the condition.
In the past, it was difficult or impossible to diagnose osteoarthritis before symptoms began to appear, but Sahu’s work has focused on finding ways to detect and diagnose osteoarthritis in its early stages and how it can be determined. Mention covers what is known. as biomarkers.
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Different methods of diagnosing osteoarthritis have their own advantages and disadvantages. Common diagnostic methods include X-rays or magnetic resonance imaging, which look at specific joints for signs of tissue damage.
“This typically occurs in the mid to late stages of osteoarthritis, when tissue damage has already occurred.”
However, biomarkers offer a unique advantage: “Biomarkers help detect changes in the course of a disease early when efforts can be made to control the disease.”
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As defined from the medical resource Cancer.gov, a tumor is “cells found in blood, fluid, or other tissues that represent a normal or abnormal process, or of a nature or disease. .”
In the simplest terms, a biomarker is an indicator of what is happening in the body, at a specific level that only the images mentioned above cannot envy.
By using single-cell technology, leading researchers like Sahu are able to identify any changes that could be a sign of disease progression.
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Also, if osteoarthritis is diagnosed in its early stages, there are many types of treatment for the patient. Cell technology is also driving the testing of potential drug therapies. Instead of testing the drug on patients with osteoarthritis, the drug could be tested on tissues removed from the patient.
These tissues would not be useful for experiments if researchers still relied solely on X-ray and MRI images, but with the ability to study genes and cellular events, these samples could provide detailed information on how these drugs affect the core of osteoarthritis.
Sahu has made great progress in his research, but of course, much remains to be done.
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The nature of this disease makes it more difficult to diagnose and more difficult to achieve. However, progress so far is tangible, as Sahu explains in this statement:
I have learned that finding common associations in different patient records is crucial in identifying potential biomarkers or targets. These groups can be obtained by stratifying patients by symptom or phenotype.
This understanding helps narrow down the search for solutions, and every step forward is encouraging when working with such a difficult disease.
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Sahu and her colleagues are using cutting-edge technology to great effect in their research, and it is likely that single-cell techniques will allow for more research and treatments in the coming months. and next year.
I am a fan of contemporary art, especially its ability to transcend the realms of art and social justice. Events are always changing and we need to change with them. Medical science continues to make great strides in the study and treatment of various diseases and health conditions.
Rarely do we have the opportunity to speak directly with a medical examiner, but last week we did.
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As we often do when we talk to experts, we asked this researcher about her real work, what is happening in the world, and her sources of motivation and inspiration. .
We invite you to join us for an interesting look at the field of medical research and the work of a professional researcher.
Neety Sahu is currently working as a postdoctoral fellow in biochemistry and osteopathy at the world-renowned Stanford University.
Postdoctoral Researcher Neety Sahu On Helping Patients With Osteoarthritis
Sahu has a PhD and to date, she has published dozens of excellent research articles in peer-reviewed scientific journals, which would be a huge achievement for even a seasoned researcher. experience.
Of course, Sahu’s work is very technical, but for the rest of the article we will do our best to link all these technical aspects with the main goal of this research, which is to help The life of people with osteoarthritis is easier.
Of course, this research could also lead to better treatments for osteoarthritis in the future, which is good news for anyone at risk for the condition.
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When and why Sahu chose to specialize in this area of medical research, the answer is simple.
Sahu specialized in osteoarthritis during graduate school. During her predoctoral and doctoral studies, she studied bone tissue (especially bone and cartilage), so it seemed inevitable that she would end up studying bone disease. Of course, osteoarthritis is one such disease.
“I’m most interested in this experience because there’s no cure, no blood test for osteoarthritis after years of research in this area. Often the device urgency is overlooked when it comes to us. growing old talking,
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